Genetic assessment and family history screening
Genomic medicine (the use of a person’s individual DNA to inform about disease risk and how to treat) is increasingly playing a central part in how we view and treat breast cancer. It can enable us to identify individuals at a higher risk of developing breast cancer so a person can know their risk but also what to do with that information to reduce their risk.
In partnership with MUMS I offer 2 gene tests. These tests include Invitae BRCA Breast Cancer STAT Panel and AnteBC Test. The two tests provide different information. As a result, they can be used together and I can advise you as to whether one or both tests will be most useful for you.
Invitae BRCA STAT Panel
Some specific rare gene defects can significantly increase an individual’s risk of developing breast cancer. To identify the risk of breast cancer, our breast surgery consultations provide Invitae BRCA STAT Panel screening to determine whether the BRCA 1 and BRCA 2 genes are present. If an individual has either of the genes associated with breast cancer, breast surgery consultations are provided to discuss what this means and how this can be managed.
This test is best for women who have:
- Had breast cancer and want to know if they are at extra risk of developing breast cancer in the other breast
- Have a strong family history of breast cancer, making it a little more likely they may have one of these nine gene defects in their DNA
- In combination with the AnteBC Test in those women with a strong or moderate family history of breast cancer, to give them an individual risk of developing breast cancer.
Recommended to women between the ages of 30 and 75, the AnteBC test determines the risk of developing breast cancer.
Reviewing DNA for any specific variations associated with breast cancer, this AnteBC test is suitable for women who do not have a family history of breast cancer but wish to know their risk of developing breast cancer at some point in their life. Based on any variations identified, the AnteBC test produces a score that outlines each individual’s risk of developing breast cancer in the next ten years compared to the average woman of their age in the population.
This score does not ascertain whether breast cancer will be experienced. Instead, it describes an individual’s chance of developing breast cancer. It should also be noted that this score does not determine whether relatives are at increased risk. The risk score is also not something that can be passed onto children. Consultations combine test results and risk factors to provide clients with a bespoke guide.
This test is best for women who do not have a strong family history of breast cancer but still want to know their risk of breast cancer.